Drug Delivery

New RA drugs and pipeline developments to watch

While there have been many therapeutic advancements in drugs for rheumatoid arthritis (RA), it is still a condition without a cure. The primary aim of medications for RA thus becomes a slowing down of the progression of the disease or reaching remission by minimizing joint pain and improving quality of life.

A range of medications with different mechanisms of action compete in the RA marketplace, starting with the tried-and-true, anchor product methotrexate. Approved in 1988 to treat RA, it is a disease-modifying antirheumatic drug (DMARD), which suppresses the immune system and can be even more efficacious when combined with other RA medications.

A trio of biologics hit the market around the turn of the century—Humira (adalimumab), Remicade (infliximab) and Enbrel (etanercept), all TNF (tumor necrosis factor) inhibitors in 1998, 1999 and 2002, respectively. TNFs suppress the physiologic response to tumor necrosis factor, which is part of an inflammatory response.

JAK inhibitors—the first one approved for RA patients was Xeljanz (tofacitinib) from Pfizer in 2012—have picked up the slack for some patients who have an inadequate response to DMARDs.


Read More http://managedhealthcareexecutive.modernmedicine.com/managed-healthcare-executive/news/new-ra-drugs-and-pipeline-developments-watch

By Mari Edlin

One of the largest companies in the world in business media

In more than 30 countries where it organizes events, UBM builds lasting relationships with specialists and key players in the market and generates opportunities that kick-start and stimulate the development of local industry on a global scale.

Read More


I accept receive communications from the promoter and partners.
Yes, I read and agree with the UBM Privacy Policy

© 2015 Hospitalar. All Rights Reserved. É proibida a reprodução do conteúdo desta página em qualquer meio de comunicação, impresso ou eletrônico, sem a autorização escrita da Hospitalar Feiras e Congressos.
Designed By Event Technology Group